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Adobe Premiere Pro 1.5 Studio Techniques

Tight deadlines and tighter budgets define digital video production today--a fact Adobe has acknowledged and responded to with its completely revamped Windows XP-only Premiere Pro video editing software. By focusing on a single (non-Mac) version of Premiere, Adobe has been able to deliver a product that raises the bar for desktop digital video editing; this approachable, complete volume gets readers beyond the basics. Offering in-depth explanations guaranteed to make the knowledge stick (and in an easygoing style that makes the book fun to read), filmmaker and Premiere whiz Jacob Rosenberg focuses on the concepts, features, and techniques that are key to mastering Adobe Premiere Pro. If you're a novice user, you'll get the grounding you need to begin capturing, editing, and outputting digital video. And if you're a Premiere veteran, you can go straight to the comprehensive coverage of all that's new: three-point color correction, multiple timelines, a new audio mixer, enhanced media management, and more. The accompanying DVD includes project files, sample footage, Third Party Plug-ins and an hour of video tutorials that help articulate concepts and features that are better suited for video explanations than on a page. "Jacob's skills and enthusiasm as an editor have been an invaluable resource to the product team throughout the development lifecycle of Premiere Pro. It is no understatement to say that he has been instrumental in charting the course of this application. His knowledge is seemingly without limit, as can be attested to by anyone who has watched him present his master classes at various tradeshows across the globe. I can think of no one better as a guide through the intricacies and depths of Premiere Pro 1.5--the best version of Premiere to date."--Richard Townhill, Group Product Manager, Adobe Video Products.

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Adobe Premiere Pro 2.0 : studio techniques

Ready to discover not just the how, but also the why behind some of the most powerful features in Premiere Pro? In Adobe Premiere Pro 2.0 Studio Techniques, author Jacob Rosenberg goes beyond conventional stepby- step instruction to give you a real-world perspective on editing with Premiere Pro. Using Jacob's fi lm footage or your own, you'll learn to deliver professional-quality results. Whether you're looking for advice on editing, effects, titles, or working with audio, this easy-to-read guide will help you add more punch to your productions. * New features in Premiere Pro 2.0: Native HD support, native HDV editing, 24P/24PA support, DVD authoring from the timeline, expedited reviewing with Adobe Clip Notes-it's all here. Find out how Premiere Pro has been improved, what's been added, and how to use new features. * Working fundamentals: From capturing video to assembling your project to the new, panel-based user interface, get an under-the-hood understanding of this powerful application. * Advanced techniques: Through hands-on lessons, learn the ins and outs of color correction, color matching, multiple-camera editing, dynamic photomontages, titling, audio and video effects, sound mixing, professional workflows for feature films and HD productions, and more. * Companion DVD: You'll fi nd extra chapters and bonus reference material to read, video tutorials to watch, media fi les to use with the book's lessons, tryout versions of Adobe Premiere Pro 2.0 and Adobe Audition 2.0, and indispensable plug-ins to install. Jacob Rosenberg is a Los Angeles-based independent filmmaker who has directed nationally broadcast commercials, music videos for such groups as the Baha Men, and several short films. Recently, Jacob has worked as a post-production supervisor on a number of feature films that used high-definition video as their digital intermediate format. A current member of the Adobe Premiere development team, and the featured instructor for Premiere Pro on the highly acclaimed Total Training Instructional DVD series, Jacob continues to raise the bar by creating new workflows and educating others about them. From IBC in Amsterdam to NAB in Las Vegas, Jacob teaches classes around the world on using Premiere Pro and other Adobe products. "With this book and Adobe Premiere Pro, you'll have all the tools you need to create your own professional-quality movies and videos. Jacob shows you how to think like a filmmaker, get the job done, and understand the creative process from start to finish." -Steven Warner Director of Engineering, Adobe Systems Inc. "Jacob has tirelessly advanced the art of filmmaking with Premiere's ever-expanding functionality, and his book demonstrates the depth and breadth of his creative artistry and technical know-how." -Rob Legato Film director and Academy-Award-winning Visual Effects Supervisor for Titanic .

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The landscape and function of anti-cytokine autoantibodies in health and immunodeficiency [electronic resource]

A fundamental question in immunology is what accounts for the variability observed in susceptibility to infectious diseases. For the last 150 years, galvanized by Pasteur's germ theory of disease, microbiologists and immunologists have made great progress in advancing our understanding of the pathophysiology of infectious microbes. However, animal hosts with apparently identical exposures can have divergent courses of infection. This question can be appreciated by anyone who asks why one sibling falls ill with a common cold while the other does not. In the lay public, these differences are attributed to an individual having a "better immune system, " however in the scientific community we lack a significantly more sophisticated answer to this basic question. In this dissertation, I propose the hypothesis that anti-cytokine autoantibodies (ACAAs) are a factor contributing to the observed variation in susceptibility to infectious diseases. To test this hypothesis, I carried out three specific aims. First, new technologies were needed to address this question. In order to discover novel ACAAs, I developed and validated protein microarray technologies to screen for hundreds of ACAAs in hundreds of patient samples. Second, using protein microarrays and other tools, I performed deep profiling of ACAAs across multiple diseases. I screened blood samples from healthy controls and compared them to those from cohorts of patients with immunodeficiency phenotypes. I performed screens in more than a dozen different primary immunodeficiencies, including diseases with and without known causative genetic mutations and have included some of the most interesting results in this thesis. To summarize results from multiple experiments, a wide diversity of ACAAs are present in healthy individuals and patients with primary immunodeficiencies. In agreement with published findings from other laboratories, in a handful of primary immunodeficiencies, ACAAs against one or a few specific cytokines can be found at high titers and not in healthy controls. I add to this literature with the discovery of high-titer ACAAs against Type I interferon in RAG1/2 mutation-associated immunodeficiency. For some other immunodeficiencies, specific ACAAs can be found at, on average, higher levels than in healthy controls, but these ranges of reactivity still overlap with reactivities found in healthy controls. For example, our discovery of IFN- ACAAs in Immunodysregulation Polyendocrinopathy Enteropathy X-Linked (IPEX) adds to this literature. Third, association with disease does not prove causation. In order to gather evidence for a causal role of ACAAs in contributing to immune deficiency, I purified and tested the function of ACAAs in vitro for blocking activity. I found that some ACAAs, like those against IFN- in IPEX, block in vitro, while others like those found in Wiskott Aldrich Syndrome do not. Taken together, these studies demonstrate that, in health and disease, the human immune system generates a diverse antibody response that reacts against a wide spectrum of antigens, including cytokines. ACAAs, in a few rare diseases, are capable of causing disease with full penetrance. However, our studies provide preliminary evidence that ACAAs may exert partially penetrant phenotypes, including phenotypes potentially based on combinations of ACAAs. Future studies, including immunoglobulin passive transfer studies, will be useful in assessing the contributions of ACAAs to infectious and non-infectious phenotypes.