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  1. Cardiomyopathies : Realisations and Expectations

    Goodwin, J. F.
    Berlin, Heidelberg : Springer Berlin Heidelberg, 1993.

    This book links basic science and clinical research in the exciting field ofcardiomyopathies. New results of biological studies in dilated cardiomyopathy and myocarditis with their implications for treatment (including cardiac transplantations and immune therapy) are presented; molecular genetic studies on gene identification in hypertrophic cardiomyopathies are relevant to prenatal diagnosis and possibly treatment. These are some of the topics presented in this book, which is indispensable for all researchers and clinicians working in the field.This book reviews the basic knowledge about the cardiomyopathies and re-enforces the well-known definitions and classification of cardiomyopathies and specific heart muscle diseases, respectively. It emphasizes the importance of maintaining the classification into hypertrophic, dilated and restrictive cardiomyopathies, even though there are exceptions. The term "realisations" in the title is used in the sense of "achievements" and alludes to the progress in the understanding of heart muscle diseases over the last three decades and also to the areas of knowledge still not fully explored, for example, the as yet un classified putative cardiomyopathies such as arrhythmogenic right ventricular dysplasia, long QT syndrome and syndrome X. The accurate and sensitive identification of major risk factors for sudden death in hypertrophic cardiomyopathy needs further study, as do the implications of a familial basis in some patients with dilated cardio myopathy. The "expectations" mentioned in the title centre around the molecular biological aspects of viral myocarditis and dilated cardio myopathy and their relationship to each other; around the auto immune basis for dilated cardiomyopathy and its implications for drug therapy and cardiac transplantation; and around molecular genetic techniques for identifying the genes involved in hypertrophic cardiomyopathy that will be developed further. These will have implications for pre-natal recognition and for diagnosis in early life in apparently fit and active persons, and offer better prospects of prevention and cure.

    Online SpringerLink

  2. Cardiomyopathies [digital] : Realisations and Expectations

    Goodwin, J. F.
    Berlin, Heidelberg : Springer Berlin Heidelberg, 1993.

    This book links basic science and clinical research in the exciting field ofcardiomyopathies. New results of biological studies in dilated cardiomyopathy and myocarditis with their implications for treatment (including cardiac transplantations and immune therapy) are presented; molecular genetic studies on gene identification in hypertrophic cardiomyopathies are relevant to prenatal diagnosis and possibly treatment. These are some of the topics presented in this book, which is indispensable for all researchers and clinicians working in the field.

    Online link.springer.com

  3. Familial cardiomyopathies : methods and protocols

    New York, NY : Humana Press, [2024]

    This volume covers the latest advances in technologies that look at familial cardiomyopathies in greater detail, and provides new computational and experimental models that model, study, and detect disease at earlier stages. Together, this allows interdisciplinary research experiments to provide new insights for the development of novel interventions that slow, stop, or even reverse the disease process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and practical, Familial Cardiomyopathies: Methods and Protocols aims to inspire further development of techniques used to study myocardial disease and the development of new, sarcomere-targeted therapeutic approaches for the maintenance of heart health and the treatment of heart failure. .

    Online SpringerLink

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